Services

Post-Colposcopy Discharge

For patients discharged from colposcopy with HPV test results available:

Negative HPV Test Result

  • Low risk for cervical cancer.

  • Return to routine screening with cytology (every three years for most people).

Positive HPV Test Result

  • Elevated risk for cervical cancer.

  • Screen with cytology annually.

Discharged With Unknown HPV Status

Multiple Normal or Negative Cytology Results (NILM)

  • Low risk for cervical cancer.

  • Return to routine screening with cytology (every three years for most people).

Combination of ASCUS, LSIL, and/or Normal Cytology

  • Elevated risk for cervical cancer.

  • Screen with cytology annually.

Resuming Routine Screening Every 3 Years

Patients can resume screening every three years when:

  • They have a negative HPV test result.

  • In the absence of HPV testing, they have three consecutive normal yearly cytology results.

  • Their risk returns to that of the general population or lower.

Re-Referral of the Colposcopy

When Should Discharged Patients Be Re-Referred to the Colposcopy?

Most patients return to routine screening intervals, typically every three years. However, those who are screened annually due to elevated risk need re-referral based on Ontario Cervical Screening Program guidance.

When Should Patients Be Referred to Colposcopy Based on Cytology Results?

Patients should be referred to colposcopy in the following cases:

  • Two consecutive ASCUS (Atypical Squamous Cells of Undetermined Significance) results.

  • Two consecutive LSIL (Low-grade Squamous Intraepithelial Lesion) results.

  • HSIL (High-grade Squamous Intraepithelial Lesion) cytology.

  • ASC-H (Atypical Squamous Cells, cannot exclude HSIL) cytology.

  • Atypical glandular cells (AGC-NOS, AGCN) cytology.

  • Adenocarcinoma in situ (AIS) cytology.

What is the Recommended Management for First-Time LSIL Results?

First-time LSIL results can be managed in primary care with repeat cytology in 12 months. Abnormal repeat results warrant further evaluation, including referral to colposcopy.

Colposcopy Indications

Pap Test Result: Atrophy

Follow-Up Recommendation:

  • Atrophy is a normal clinical state.

  • No increased risk of high-grade dysplasia or cervical cancer.

  • Action only if clinically necessary (e.g., for vaginal symptoms or cytology reevaluation).

Pap Test Result: Benign Endometrial Cells

Follow-Up Recommendation:

  • Routine finding; typically, no action required.

  • Pre-menopausal asymptomatic patients continue usual screening.

  • Post-menopausal patients require investigations (imaging or endometrial tissue sampling).

  • Any patient with abnormal vaginal bleeding needs appropriate investigation.

Pap Test Result: “Transformation Zone Components Not Present”

Follow-Up Recommendation:

  • The absence of transformation zone (T-zone) components alone doesn't require earlier rescreening.

  • Patients with satisfactory cytology evaluation and negative for intraepithelial lesion or malignancy (NILM) but lacking T-zone components should be re-tested at regular screening intervals.

  • Patients with abnormal cervical cytology should follow screening recommendations regardless of T-zone components.

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